Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20687914 | 0.93 | TYK2 (0.56) | TYK2PDE4DJAK1 | |
| SCHEMBL20689444 | 0.89 | TYK2 (0.52) | TYK2PDE4DJAK1 | |
| SCHEMBL20689636 | 0.87 | TYK2 (0.49) | TYK2PDE4DJAK1 | |
| SCHEMBL20688947 | 0.86 | TYK2 (0.73) | TYK2PDE4DJAK1 | |
| SCHEMBL20696806 | 0.85 | TYK2 (0.71) | TYK2PDE4D | |
| SCHEMBL20689205 | 0.85 | TYK2 (0.71) | TYK2PDE4D | |
| SCHEMBL20696977 | 0.85 | TYK2 (0.71) | TYK2PDE4D | |
| SCHEMBL20697381 | 0.85 | TYK2 (0.55) | TYK2PDE4DJAK1 | |
| SCHEMBL20689161 | 0.84 | TYK2 (0.61) | TYK2PDE4D | |
| SCHEMBL25069838 | 0.84 | TYK2 (0.72) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023468-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2019-01-31 | — | — | WO | disclosed |