Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760241 | 0.72 | — | — | |
| SCHEMBL2441885 | 0.72 | — | — | |
| SCHEMBL2947618 | 0.70 | TSHR (0.31) | TSHR | |
| SCHEMBL11706686 | 0.70 | — | — | |
| SCHEMBL27806828 | 0.70 | TSHR (0.36) | ALDH1A1TSHR | |
| SCHEMBL23233853 | 0.70 | — | — | |
| SCHEMBL28007795 | 0.68 | — | — | |
| SCHEMBL25068519 | 0.68 | — | — | |
| SCHEMBL21084308 | 0.67 | — | — | |
| SCHEMBL21142355 | 0.67 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023468-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2019-01-31 | — | — | WO | disclosed |