Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24060657 | 0.91 | SLC29A1 (0.32) | SLC29A1 | |
| SCHEMBL20692234 | 0.88 | CNR2 (0.32) | SLC29A1 | |
| SCHEMBL24680745 | 0.87 | SLC29A1 (0.32) | SLC29A1 | |
| SCHEMBL20691367 | 0.83 | SLC29A1 (0.51) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL20692028 | 0.81 | SLC29A1 (0.47) | SLC29A1LMNAALDH1A1ALBMAPK1 | |
| SCHEMBL22349184 | 0.81 | SLC29A1 (0.47) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL25688810 | 0.79 | SLC29A1 (0.45) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL25688811 | 0.74 | SLC29A1 (0.36) | SLC29A1LMNARAB9ACYP3A4PKM | |
| SCHEMBL24322061 | 0.72 | POLA1 (0.32) | — | |
| SCHEMBL24680579 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658565-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |
| WO-2019023459-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-31 | — | — | WO | disclosed |