Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | BMP1 | P13497 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.31 |
| ▸ | FNTB | P49356 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27267642 | 0.85 | GNPAT (0.44) | GNPATMMEACEBMP1CA2 | |
| SCHEMBL10036415 | 0.84 | ECE1 (0.41) | — | |
| SCHEMBL10036293 | 0.84 | ECE1 (0.41) | — | |
| SCHEMBL27267745 | 0.83 | GNPAT (0.46) | GNPATMMEBMP1CA2CA4 | |
| SCHEMBL13377669 | 0.83 | GNPAT (0.46) | GNPATMMEBMP1CA2CA4 | |
| SCHEMBL24239570 | 0.82 | BIRC2 (0.41) | LTA4HMME | |
| SCHEMBL25602934 | 0.82 | FOLH1 (0.43) | BMP1 | |
| SCHEMBL25602938 | 0.82 | FOLH1 (0.43) | BMP1 | |
| SCHEMBL25602931 | 0.82 | FOLH1 (0.43) | BMP1 | |
| SCHEMBL25602936 | 0.82 | FOLH1 (0.43) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132588-A1 | COMBINATION THERAPY OF ARMS AND NATURAL KILLER CELLS | KLEO PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2019023501-A1 | UNIVERSAL ABT COMPOUNDS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-01-31 | — | — | WO | disclosed |