Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 18/20 | 0.81 |
| ▸ | PSMB8 | P28062 | 8/20 | 0.81 |
| ▸ | PSMB9 | P28065 | 8/20 | 0.81 |
| ▸ | PSMB6 | P28072 | 8/20 | 0.81 |
| ▸ | PSMB10 | P40306 | 8/20 | 0.81 |
| ▸ | PSMB11 | A5LHX3 | 7/20 | 0.81 |
| ▸ | PSMA7 | O14818 | 7/20 | 0.81 |
| ▸ | PSMB1 | P20618 | 7/20 | 0.81 |
| ▸ | PSMA1 | P25786 | 7/20 | 0.81 |
| ▸ | PSMA2 | P25787 | 7/20 | 0.81 |
| ▸ | PSMA3 | P25788 | 7/20 | 0.81 |
| ▸ | PSMA4 | P25789 | 7/20 | 0.81 |
| ▸ | PSMA5 | P28066 | 7/20 | 0.81 |
| ▸ | PSMB4 | P28070 | 7/20 | 0.81 |
| ▸ | PSMB3 | P49720 | 7/20 | 0.81 |
| ▸ | PSMB2 | P49721 | 7/20 | 0.81 |
| ▸ | PSMA6 | P60900 | 7/20 | 0.81 |
| ▸ | PSMA8 | Q8TAA3 | 7/20 | 0.81 |
| ▸ | PSMB7 | Q99436 | 7/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ixazomib SCHEMBL3742758 | 0.88 | PSMB5 (1.00) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| Ixazomib SCHEMBL29353014 | 0.88 | PSMB5 (1.00) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| Ixazomib SCHEMBL18088836 | 0.88 | PSMB5 (1.00) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL21841184 | 0.88 | PSMB5 (0.80) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL252153 | 0.86 | PSMB5 (0.81) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL21977965 | 0.84 | PSMB5 (0.58) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL29768798 | 0.84 | PSMB5 (0.58) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL4796314 | 0.83 | PSMB5 (0.74) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL20694721 | 0.83 | PSMB5 (0.81) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL3753435 | 0.83 | PSMB5 (0.85) | PSMB5PSMB8PSMB9PSMB6PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851108-B1 | BORATE-BASED DRUG AND USE THEREOF | CHENGDU ORIGIN BIOTECHNOLOGY LTD COMPANY (CN) | 2023-08-09 | — | — | EP | disclosed |
| EP-3851108-A1 | BORATE-BASED DRUG AND USE THEREOF | Chengdu Origin Biotechnology Limited Company (CN) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020052488-A1 | BORATE-BASED DRUG AND USE THEREOF | 成都奥璟生物科技有限公司 | 2020-03-19 | — | — | WO | disclosed |
| WO-2019020099-A1 | BORATE COMPOUND, AND SYNTHESIS METHOD THEREFOR AND USES THEREOF | 成都地奥九泓制药厂 | 2019-01-31 | — | — | WO | disclosed |