SCHEMBL2069663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15630880	1.00	DPP4 (0.51)	DPP4MYCPIM1PIM3PIM2
	SCHEMBL26103588	0.92	MYC (0.49)	DPP4MYCPIM1PIM3PIM2
	SCHEMBL28989190	0.90	NPC1 (0.48)	DPP4MYCNPC1SMN1; SMN2KDM4E
	SCHEMBL15630869	0.85	GAA (0.53)	MYCSMN1; SMN2KDM4EALDH1A1MEN1
	SCHEMBL23611760	0.84	MYC (0.47)	MYCNPC1SMN1; SMN2KDM4EALDH1A1
	SCHEMBL2069713	0.84	RPS6KB1 (0.46)	DPP4MYCPIM1PIM3PIM2
	SCHEMBL11908438	0.83	NPC1 (0.65)	PIM1PIM3PIM2NPC1MAP4K1
	SCHEMBL2070104	0.83	NOTUM (0.53)	MYCSMN1; SMN2KDM4EALDH1A1MEN1
	SCHEMBL2069146	0.82	PTPN1 (0.56)	MYCNPC1SMN1; SMN2KDM4EALDH1A1
	SCHEMBL23708768	0.81	NPC1 (0.60)	MYCNPC1SMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.