SCHEMBL2069716

SCHEMBL2069716

Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)NCC1CN(c2ccccc2C(=O)OC(C)(C)C)CCO1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.63
CHRM4 P08173 3/20 0.48
PPARD Q03181 3/20 0.45
GAA P10253 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PPARG P37231 1/20 0.40
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2069374 0.90 PPARA (0.73) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2069412 0.83 PPARA (0.61) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2069714 0.82 PPARA (0.41) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2069727 0.80 PPARA (0.65) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2069611 0.79 PPARA (0.86) PPARACHRM4PPARDPPARG
SCHEMBL2069330 0.78 PPARA (0.66) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2069990 0.78 PPARA (0.67) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2071325 0.76 PPARA (0.46) PPARACHRM4PPARDGAAALDH1A1
SCHEMBL2069034 0.75 PPARA (0.73) PPARACHRM4PPARDGAASMN1; SMN2
SCHEMBL2070819 0.75 PPARA (0.73) PPARACHRM4PPARDGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902367-B2 Cyclic amino benzoic acid derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2011-03-08 US disclosed
US-7902367-B2 Cyclic amino benzoic acid derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2011-03-08 US disclosed
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-10-25 US disclosed
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-10-25 US disclosed
EP-1780210-A1 NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE Kyorin Pharmaceutical Co., Ltd. (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative PPARA, PPARG, PPARD PPARA 1/4885CHRM4 966/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.