Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | IL6ST | P40189 | 4/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576421 | 0.85 | PIK3CD (0.71) | PIK3CDIL6STSTAT3ARIDH1 | |
| SCHEMBL11949263 | 0.85 | PIK3CD (0.71) | PIK3CDIL6STSTAT3ARIDH1 | |
| SCHEMBL11949264 | 0.85 | PIK3CD (0.71) | PIK3CDIL6STSTAT3ARIDH1 | |
| SCHEMBL2036191 | 0.80 | PIK3CD (0.50) | PIK3CDIL6STSTAT3GAAAR | |
| SCHEMBL21142845 | 0.74 | PIK3CD (0.43) | PIK3CDIL6ST | |
| SCHEMBL24983622 | 0.71 | PIK3CD (0.67) | PIK3CDIL6STSTAT3ARIDH1 | |
| SCHEMBL27326397 | 0.71 | PIK3CD (0.49) | PIK3CDIL6STSTAT3GAAAR | |
| SCHEMBL15013873 | 0.71 | — | — | |
| SCHEMBL2631378 | 0.71 | — | — | |
| SCHEMBL15134202 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019022600-A1 | TREATING PATHOLOGICAL CONDITIONS BY DIRECT AND INDIRECT TARGETING OF SIRPA - CD47 INTERACTION | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis (NL) | 2019-01-31 | — | — | WO | disclosed |