SCHEMBL20697491

SCHEMBL20697491

Cc1ccc(N/C(=N\N)NCCCn2cncc2C)cc1C

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3643607 0.86 QPCT (0.67) QPCT
SCHEMBL8193472 0.83 QPCT (0.57) QPCT
SCHEMBL22753653 0.78 QPCT (0.56) QPCT
SCHEMBL29410579 0.77 QPCT (1.00) QPCT
SCHEMBL11892028 0.74 QPCT (0.68) QPCT
SCHEMBL3638535 0.74 QPCT (0.54) QPCT
SCHEMBL8187276 0.74 QPCT (0.54) QPCT
SCHEMBL3644554 0.73 QPCT (0.54) QPCT
SCHEMBL11892022 0.72 QPCT (0.52) QPCT
SCHEMBL3634722 0.72 QPCT (0.52) QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019022600-A1 TREATING PATHOLOGICAL CONDITIONS BY DIRECT AND INDIRECT TARGETING OF SIRPA - CD47 INTERACTION Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis (NL) 2019-01-31 WO disclosed