Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173553 | 0.73 | PDE2A (0.47) | PDE2APDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL20698143 | 0.72 | PDE2A (0.36) | PDE2APDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL1724939 | 0.71 | PDE10A (0.41) | PDE2APDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL20698179 | 0.69 | PDE10A (0.39) | PDE2APDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL1725188 | 0.68 | MAPT (0.49) | — | |
| SCHEMBL24158238 | 0.68 | HSP90AA1 (0.37) | — | |
| SCHEMBL173584 | 0.68 | PDE10A (0.47) | PDE2APDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL24158349 | 0.67 | HSP90AA1 (0.37) | PDE2A | |
| SCHEMBL20698206 | 0.67 | PDE10A (0.39) | PDE2APDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL1726288 | 0.66 | PDE2A (0.39) | PDE2APDE10AGRM8CYP1A2GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019020981-A1 | PYRAZOLE, ISOTHIAZOLE AND ISOXAZOLE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | REDAG CROP PROTECTION LTD. (GB) | 2019-01-31 | — | — | WO | disclosed |