SCHEMBL20699048

SCHEMBL20699048

CO/C=C(/C(=O)OC)c1ccccc1CO/N=C(\N)c1snc(Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 5/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.32
▸ RAB9A P51151 3/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ HPGD P15428 1/20 0.31
▸ NPC1 O15118 2/20 0.31
▸ PKM P14618 2/20 0.31
▸ MITF O75030 1/20 0.31
▸ PTGS2 P35354 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20698620 0.91 HIF1A (0.34) HIF1APTGS2
SCHEMBL20698887 0.88 HIF1A (0.32) HIF1APTGS2
SCHEMBL20698666 0.85 HIF1A (0.48) HIF1AL3MBTL1RAB9ASMN1; SMN2HPGD
SCHEMBL20698903 0.82 HIF1A (0.33) HIF1AL3MBTL1SMN1; SMN2TDP1
SCHEMBL20699051 0.82 HIF1A (0.31) HIF1APTGS2
SCHEMBL20698886 0.81 HIF1A (0.30) HIF1A
SCHEMBL20699003 0.79 HIF1A (0.38) HIF1APTGS2
SCHEMBL18292032 0.76 HIF1A (0.39) HIF1APTGS2
SCHEMBL20698622 0.76 HIF1A (0.50) HIF1APTGS2
SCHEMBL20699002 0.76 HIF1A (0.36) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10906880-B2 Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application NANKAI UNIVERSITY (CN) 2021-02-02 — — US disclosed
US-20190031627-A1 A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION NANKAI UNIVERSITY (CN) 2019-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10906880-B2 Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application STS, STAU1, CDV3 HIF1A 3135/4885L3MBTL1 2684/4885RAB9A 3363/4885
US-20190031627-A1 A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION STS, CDV3, SALL4 HIF1A 3136/4885L3MBTL1 2750/4885RAB9A 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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