SCHEMBL2069992

SCHEMBL2069992

Cc1nc(-c2ccc(Cl)cc2)sc1CNC(=O)[C@H]1CCCN(c2ccccc2C(=O)O)C1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 7/20 0.56
MAPT P10636 6/20 0.49
GPBAR1 Q8TDU6 2/20 0.46
TP53 P04637 4/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.45
THRB P10828 1/20 0.45
PPARG P37231 1/20 0.45
PPARD Q03181 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2069318 1.00 PPARA (0.56) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL2072276 1.00 PPARA (0.56) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL2069037 0.93 PPARA (0.51) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL3893838 0.89 PPARA (0.52) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL3890836 0.86 PPARA (0.49) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL14528288 0.83 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL2069175 0.83 PPARA (0.71) PPARAMAPTLMNAPOLBPPARG
SCHEMBL3903528 0.82 PPARA (0.46) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL3903526 0.82 PPARA (0.46) PPARAMAPTGPBAR1TP53LMNA
SCHEMBL5189321 0.82 PPARA (0.72) PPARAPOLBPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-10-25 US claimed
EP-1780210-A1 NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE Kyorin Pharmaceutical Co., Ltd. (JP) 2007-05-02 EP claimed
US-7902367-B2 Cyclic amino benzoic acid derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2011-03-08 US disclosed
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2007-10-25 US disclosed
EP-1780210-A1 NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE Kyorin Pharmaceutical Co., Ltd. (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249580-A1 Novel Cyclic Amino Benzoic Acid Derivative PPARA, PPARG, PPARD PPARA 1/4885MAPT 4544/4885GPBAR1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.