Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069341 | 0.87 | BIRC5 (0.63) | BIRC5PIM1 | |
| SCHEMBL2069742 | 0.87 | BIRC5 (0.68) | BIRC5 | |
| SCHEMBL2070100 | 0.81 | BIRC5 (0.63) | BIRC5 | |
| SCHEMBL2070251 | 0.81 | BIRC5 (0.64) | BIRC5 | |
| SCHEMBL2070174 | 0.80 | BIRC5 (0.63) | BIRC5 | |
| SCHEMBL2071285 | 0.80 | BIRC5 (0.68) | BIRC5 | |
| SCHEMBL2071630 | 0.79 | BIRC5 (0.73) | BIRC5 | |
| SCHEMBL2072312 | 0.79 | BIRC5 (0.63) | BIRC5 | |
| SCHEMBL2070344 | 0.79 | BIRC5 (0.63) | BIRC5 | |
| SCHEMBL2071140 | 0.78 | BIRC5 (0.66) | BIRC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910742-B2 | Survivin inhibitors | ABBOTT LABORATORIES (US) | 2011-03-22 | — | — | US | disclosed |
| US-20070072833-A1 | Survivin inhibitors | ABBVIE INC. | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072833-A1 | Survivin inhibitors | XIAP, BIRC5, BIRC3 | BIRC5 2/4885PIM1 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.