⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394210 | 0.69 | — | — | |
| SCHEMBL2260001 | 0.69 | — | — | |
| SCHEMBL102331 | 0.67 | PDPK1 (0.59) | — | |
| Bromide SCHEMBL7850 | 0.67 | — | — | |
| SCHEMBL28395511 | 0.67 | — | — | |
| Aminothiazole SCHEMBL1136755 | 0.65 | — | — | |
| SCHEMBL6063 | 0.65 | — | — | |
| Aminothiazole SCHEMBL7401 | 0.65 | — | — | |
| SCHEMBL31556353 | 0.65 | PDPK1 (0.56) | — | |
| SCHEMBL31083943 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1058 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336961-B | Thiazolyl sulfur-rich covalent organic framework and preparation method and application thereof | 山西大同大学 | 2023-03-10 | — | — | CN | claimed |
| CN-110655526-A | Cephalosporin-siderophore conjugates and methods of preparation and use thereof | 中国科学院上海药物研究所 | 2020-01-07 | — | — | CN | claimed |
| EP-2640687-B1 | 4-SUBSTITUTED-3-BENZYLOXY-BICYCLO[3.1.0]HEXANE COMPOUNDS AS mGluR 2/3 ANTAGONISTS | LILLY CO ELI (US) | 2018-06-27 | — | — | EP | claimed |
| US-10000450-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-06-19 | — | — | US | claimed |
| US-20170166524-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-06-15 | — | — | US | claimed |
| US-9611214-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-04-04 | — | — | US | claimed |
| US-9056844-B2 | 4-substituted-3-benzyloxy-bicyclo[3.1.0]hexane compounds as mGluR 2/3 antagonists | ELI LILLY AND COMPANY (US) | 2015-06-16 | — | — | US | claimed |
| US-20140288065-A1 | N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-09-25 | — | — | US | claimed |
| US-8815871-B2 | N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-08-26 | — | — | US | claimed |
| EP-2640687-A1 | 4-SUBSTITUTED-3-BENZYLOXY-BICYCLO[3.1.0]HEXANE COMPOUNDS AS mGluR 2/3 ANTAGONISTS | Eli Lilly and Company (US) | 2013-09-25 | — | — | EP | claimed |
| EP-0022245-A2 | Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-01-14 | — | — | EP | claimed |
| EP-0016296-A1 | Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | claimed |
| US-4200744-A | Substituted 7α-methoxy-7β[(2,3-dioxo-1-piperazinyl)carbonylaminophenylacetamido]cephalosporins | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1980-04-29 | — | — | US | claimed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | claimed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | claimed |
| EP-0000500-A2 | Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |
| US-4066641-A | METHOD FOR CYCLIZATION TO GIVE CEPHEM RING | HAMASHIMA YOSHIO | 1978-01-03 | — | — | US | claimed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | claimed |
| US-4012372-A | MONOAZO DISPERSE DYES | EASTMAN KODAK COMPANY (US) | 1977-03-15 | — | — | US | claimed |
| US-3980634-A | Phthalimidyl-azo aniline type compounds and polyester fibers dyed therewith | EASTMAN KODAK COMPANY (US) | 1976-09-14 | — | — | US | claimed |