Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705166 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705163 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705277 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705158 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705120 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705119 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705156 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705157 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705159 | 1.00 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20713740 | 1.00 | KLKB1 (0.80) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661922-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | Dyax Corp. (US) | 2020-06-10 | — | — | EP | disclosed |
| WO-2019028362-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2019-02-07 | — | — | WO | disclosed |