Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 3/20 | 0.33 |
| ▸ | HK2 | P52789 | 3/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 3/20 | 0.30 |
| ▸ | PYGB | P11216 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21003643 | 0.82 | OGA (0.40) | AMDHD2OGAFBP1 | |
| SCHEMBL14117224 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL14149372 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL889845 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL3441538 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL3441539 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL8321727 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL5358194 | 0.80 | OGA (0.41) | AMDHD2OGAFBP1ADORA3ADK | |
| SCHEMBL4314010 | 0.80 | MAPK1 (0.49) | AMDHD2KDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL18391246 | 0.80 | MAPK1 (0.49) | AMDHD2KDM4ELMNACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10197707-B2 | Ophthalmic devices comprising photochromic materials with reactive sub substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-02-05 | — | — | US | disclosed |