Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.88 |
| ▸ | RAB9A | P51151 | 2/20 | 0.88 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760286 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL11756315 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL9489987 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL11761105 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL11754310 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL11755990 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL11758269 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL11759659 | 0.94 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 | |
| SCHEMBL16508693 | 0.89 | NPC1 (0.73) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL24420725 | 0.88 | NPC1 (0.88) | NPC1RAB9AHPGDSMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438195-A1 | ACRYLIC POLYMER COMPOSITION | Zeon Corporation (JP) | 2019-02-06 | — | — | EP | disclosed |