Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.79 |
| ▸ | CSF1R | P07333 | 2/20 | 0.79 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.79 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.79 |
| ▸ | ABL1 | P00519 | 5/20 | 0.69 |
| ▸ | BRAF | P15056 | 7/20 | 0.61 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | BLK | P51451 | 1/20 | 0.52 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.52 |
| ▸ | RBP4 | P02753 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 4/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20707298 | 0.89 | KIT (0.89) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391338 | 0.89 | KIT (0.66) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20707289 | 0.89 | KIT (1.00) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20695972 | 0.88 | KIT (0.78) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20695973 | 0.88 | KIT (0.75) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20695981 | 0.86 | KIT (0.86) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20695965 | 0.86 | KIT (0.75) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20707306 | 0.86 | KIT (0.79) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20707279 | 0.86 | KIT (0.79) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20695966 | 0.86 | KIT (0.79) | KITCSF1RPDGFRBDDR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793543-B2 | Selective C-KIT kinase inhibitor | PRECEDO PHARMACEUTICALS CO., LTD (CN) | 2020-10-06 | — | — | US | disclosed |
| US-20190084960-A1 | SELECTIVE C-KIT KINASE INHIBITOR | PRECEDO PHARMACEUTICALS CO., LTD (CN) | 2019-03-21 | — | — | US | disclosed |
| EP-3438094-A1 | SELECTIVE C-KIT KINASE INHIBITOR | Precedo Pharmaceuticals Co., Ltd. (CN) | 2019-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793543-B2 | Selective C-KIT kinase inhibitor | KIT, CHUK, MAP3K19 | KIT 1/4885CSF1R 395/4885PDGFRB 305/4885 |
| US-20190084960-A1 | SELECTIVE C-KIT KINASE INHIBITOR | KIT, CHUK, MAP3K19 | KIT 1/4885CSF1R 395/4885PDGFRB 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.