SCHEMBL20707447

SCHEMBL20707447

CC1(C)c2ccccc2-c2ccc(-n3c4ccc(-c5ccc(-n6c7ccccc7c7ccccc76)cc5)cc4c4cc(-c5ccc(-n6c7ccccc7c7ccccc76)cc5)ccc43)cc21

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC4 P56524 1/20 0.36
TSPO P30536 3/20 0.34
PDK2 Q15119 8/20 0.33
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
PGR P06401 4/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20707434 1.00 KDM4E (0.38) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL15436081 0.99 KDM4E (0.39) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL15480241 0.98 KDM4E (0.40) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL15696452 0.98 KDM4E (0.40) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL14212266 0.98 KDM4E (0.40) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL23370388 0.98 KDM4E (0.40) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL22876207 0.98 KDM4E (0.43) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL13444126 0.97 PDK2 (0.35) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL13443575 0.97 PDK2 (0.35) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL14900782 0.97 KDM4E (0.37) KDM4EATML3MBTL1HDAC4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3439062-B1 ORGANIC LIGHT EMITTING ELEMENT LG CHEMICAL LTD (KR) 2021-09-08 EP disclosed
US-20190148650-A1 Organic Light Emitting Device LG CHEM, LTD. (KR) 2019-05-16 US disclosed
EP-3439062-A1 ORGANIC LIGHT EMITTING ELEMENT LG Chem, Ltd. (KR) 2019-02-06 EP disclosed