Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061462 | 0.94 | NPC1 (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL816945 | 0.94 | NPC1 (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL13944904 | 0.93 | NPC1 (0.45) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL13703597 | 0.93 | HTT (0.39) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL16674100 | 0.92 | HTT (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL18803342 | 0.92 | NPC1 (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL16425803 | 0.92 | NPC1 (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL20883271 | 0.92 | NPC1 (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL17721435 | 0.92 | HTT (0.44) | HTTTDP1POLBAPEX1NPC1 | |
| SCHEMBL9106264 | 0.92 | HTT (0.44) | HTTTDP1POLBAPEX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438134-A1 | POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT | Adeka Corporation (JP) | 2019-02-06 | — | — | EP | disclosed |