Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22403072 | 0.90 | GBA1 (0.76) | GBA1 | |
| SCHEMBL20710482 | 0.86 | GBA1 (0.58) | GBA1 | |
| SCHEMBL20710511 | 0.85 | GBA1 (0.80) | GBA1 | |
| SCHEMBL20710486 | 0.77 | GBA1 (0.72) | GBA1 | |
| SCHEMBL20710420 | 0.76 | GBA1 (0.63) | GBA1 | |
| SCHEMBL20710543 | 0.75 | GBA1 (0.83) | GBA1 | |
| SCHEMBL22403117 | 0.75 | GBA1 (1.00) | GBA1 | |
| SCHEMBL20710469 | 0.75 | GBA1 (0.79) | GBA1 | |
| SCHEMBL20710440 | 0.74 | GBA1 (0.94) | GBA1 | |
| SCHEMBL20710423 | 0.74 | GBA1 (0.85) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019027765-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS AND USES THERE | NORTHWESTERN UNIVERSITY (US) | 2019-02-07 | — | — | WO | disclosed |