SCHEMBL20712908

SCHEMBL20712908

C=CC(=O)OC1CCC(OC(=O)C=C)C(OC(=O)C=C)C1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
INPP5A Q14642 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25894674 0.86 TSHR (0.33) ALDH1A1CYP3A4TSHR
SCHEMBL321481 0.81 TSHR (0.36) ALDH1A1CYP3A4TSHR
SCHEMBL34965 0.81
SCHEMBL12531250 0.80 ATM (0.33) ALDH1A1CYP3A4TSHRATM
SCHEMBL10874748 0.79 ATM (0.30) ATM
Potassium SCHEMBL31173511 0.79
SCHEMBL27696010 0.79
SCHEMBL19846626 0.78 SERPINE1 (0.41) ALDH1A1CYP3A4TSHR
SCHEMBL10750894 0.77 SERPINE1 (0.37) ALDH1A1CYP3A4TSHRATM
SCHEMBL19232241 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019025398-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2019-02-07 WO disclosed