Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.64 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705066 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20713875 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20713718 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705283 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705061 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705064 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705257 | 0.88 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL20705205 | 0.87 | KLKB1 (0.83) | KLKB1 | |
| SCHEMBL20713778 | 0.87 | KLKB1 (0.65) | KLKB1USP30 | |
| SCHEMBL22277317 | 0.87 | KLKB1 (0.65) | KLKB1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019028362-A1 | INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF | DYAX CORP. (US) | 2019-02-07 | — | — | WO | disclosed |