Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714327 | 1.00 | AOC3 (0.60) | AOC3MAOBALOX15GFERADAM17 | |
| SCHEMBL20709014 | 0.89 | AOC3 (0.61) | AOC3MAOBALOX15GFERADAM17 | |
| SCHEMBL16766984 | 0.89 | AOC3 (0.61) | AOC3MAOBALOX15GFERADAM17 | |
| SCHEMBL16766986 | 0.89 | AOC3 (0.61) | AOC3MAOBALOX15GFERADAM17 | |
| SCHEMBL20091174 | 0.79 | AOC3 (0.49) | AOC3MAOBALOX15GFERADAM17 | |
| SCHEMBL16766988 | 0.75 | AOC3 (1.00) | AOC3MAOB | |
| SCHEMBL16766991 | 0.75 | AOC3 (1.00) | AOC3MAOB | |
| SCHEMBL16767507 | 0.75 | AOC3 (1.00) | AOC3MAOB | |
| Hydrochloric Acid SCHEMBL30150869 | 0.74 | AOC3 (0.67) | AOC3MAOBLMNAMAPTNR1H4 | |
| Hydrochloric Acid SCHEMBL15528246 | 0.74 | AOC3 (1.00) | AOC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019024924-A1 | AMINE COMPOUND FOR INHIBITING SSAO/VAP-1 AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2019-02-07 | — | — | WO | disclosed |