Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 18/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714514 | 1.00 | AOC3 (0.52) | AOC3MEN1KMT2ANPC1NFKB1 | |
| SCHEMBL21889507 | 0.90 | AOC3 (0.67) | AOC3MEN1KMT2A | |
| SCHEMBL21889818 | 0.90 | AOC3 (0.64) | AOC3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20714067 | 0.86 | AOC3 (0.65) | AOC3MEN1KMT2A | |
| SCHEMBL20714066 | 0.86 | AOC3 (0.65) | AOC3MEN1KMT2A | |
| SCHEMBL20714300 | 0.86 | AOC3 (0.48) | AOC3MEN1KMT2A | |
| SCHEMBL29037060 | 0.86 | AOC3 (0.48) | AOC3MEN1KMT2A | |
| SCHEMBL21914790 | 0.85 | AOC3 (0.62) | AOC3 | |
| SCHEMBL21845108 | 0.84 | AOC3 (0.57) | AOC3 | |
| SCHEMBL21889500 | 0.84 | AOC3 (0.57) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914234-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110914234-A | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2020-03-24 | — | — | CN | disclosed |
| WO-2019024924-A1 | AMINE COMPOUND FOR INHIBITING SSAO/VAP-1 AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2019-02-07 | — | — | WO | disclosed |