⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159800 | 0.96 | KDM4E (0.32) | — | |
| SCHEMBL20159801 | 0.94 | KDM4E (0.33) | — | |
| SCHEMBL20159877 | 0.94 | KDM4E (0.33) | — | |
| SCHEMBL20159894 | 0.93 | PRKDC (0.31) | — | |
| SCHEMBL25018845 | 0.92 | — | — | |
| SCHEMBL20159806 | 0.92 | KDM4E (0.32) | — | |
| SCHEMBL20159762 | 0.92 | KDM4E (0.32) | — | |
| SCHEMBL20159447 | 0.92 | KDM4E (0.32) | — | |
| SCHEMBL30364790 | 0.92 | KDM4E (0.32) | — | |
| SCHEMBL20139057 | 0.92 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237409-B1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | MERCK PATENT GMBH (DE) | 2022-01-05 | — | — | EP | disclosed |
| US-20190044071-A1 | CARBAZOLES WITH TWO DIBENZOFURAN OR DIBENZOTHIOPHENE SUBSTITUENTS | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | US | disclosed |