Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | FES | P07332 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
| ▸ | MARK3 | P27448 | 1/20 | 0.57 |
| ▸ | TYK2 | P29597 | 1/20 | 0.57 |
| ▸ | FLT4 | P35916 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102774 | 0.86 | CYP3A4 (0.75) | CYP3A4MAPTFAAHCA1CA2 | |
| SCHEMBL16022557 | 0.85 | CYP3A4 (0.74) | CYP3A4MAPTFAAHCYP1A2CYP2C9 | |
| SCHEMBL479925 | 0.84 | CYP3A4 (0.72) | CYP3A4MAPTFESRETMARK3 | |
| SCHEMBL27507343 | 0.83 | CYP3A4 (0.71) | CYP3A4FESRETMARK3TYK2 | |
| SCHEMBL1275003 | 0.83 | CYP3A4 (0.71) | CYP3A4MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL825961 | 0.83 | CYP3A4 (0.71) | CYP3A4FAAHFLT4CA1CA2 | |
| SCHEMBL29357760 | 0.82 | CYP3A4 (0.69) | CYP3A4FAAHFESRETMARK3 | |
| SCHEMBL4603002 | 0.82 | CYP3A4 (0.69) | CYP3A4FAAHFESRETMARK3 | |
| SCHEMBL9118033 | 0.80 | CYP3A4 (0.67) | CYP3A4MAPTFAAHCA1CA2 | |
| SCHEMBL7761440 | 0.80 | MAPT (0.86) | CYP3A4MAPTFAAHFESRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190038611-A1 | Novel CYP34A-Specific Inhibitors and Methods of Using Same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190038611-A1 | Novel CYP34A-Specific Inhibitors and Methods of Using Same | CYP3A43, CYP3A4, CYP4B1 | CYP3A4 2/4885MAPT 3916/4885FAAH 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.