Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20049432 | 0.85 | STING1 (0.74) | STING1 | |
| SCHEMBL20022177 | 0.84 | STING1 (0.81) | STING1 | |
| SCHEMBL25015638 | 0.84 | STING1 (1.00) | STING1 | |
| SCHEMBL25015636 | 0.84 | STING1 (1.00) | STING1 | |
| SCHEMBL20022222 | 0.84 | STING1 (1.00) | STING1 | |
| SCHEMBL20022294 | 0.84 | STING1 (1.00) | STING1 | |
| SCHEMBL25015478 | 0.84 | STING1 (1.00) | STING1 | |
| SCHEMBL20022251 | 0.84 | STING1 (1.00) | STING1 | |
| SCHEMBL20022196 | 0.84 | STING1 (0.81) | STING1 | |
| SCHEMBL30416864 | 0.84 | STING1 (1.00) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |
| WO-2019027857-A1 | COMBINATIONS OF PD-1 ANTAGONISTS AND BENZO[b]THIOPHENE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2019-02-07 | — | — | WO | disclosed |