Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718364 | 0.89 | APP (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20718361 | 0.87 | APP (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27890469 | 0.79 | MEN1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20718460 | 0.76 | MAPT (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6421503 | 0.76 | SNCA (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6421501 | 0.76 | SNCA (0.64) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20718457 | 0.75 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL20718455 | 0.73 | HPGD (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9000333 | 0.70 | SNCA (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22955025 | 0.70 | APP (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025595-A1 | SELECTIVE LIGANDS FOR TAU AGGREGATES | KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) | 2019-02-07 | — | — | WO | disclosed |