SCHEMBL20718779

SCHEMBL20718779

CC(O)COc1ccc(C2(c3ccc(OCC(C)O)c(C(C)(C)C)c3)c3ccccc3-c3ccccc32)cc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MAPT P10636 3/20 0.38
USP2 O75604 1/20 0.37
LMNA P02545 3/20 0.37
PDK2 Q15119 3/20 0.36
TP53 P04637 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
OPRK1 P41145 1/20 0.34
CYP2C19 P33261 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
ADRB2 P07550 2/20 0.33
ADRB1 P08588 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22829526 0.86 ESR1 (0.46) ESR1ESR2MAPTLMNAPDK2
SCHEMBL14816423 0.84 ESR1 (0.54) ESR1ESR2MAPTLMNAPDK2
SCHEMBL29441932 0.84 ESR1 (0.54) ESR1ESR2MAPTLMNAPDK2
SCHEMBL20718778 0.82 ESR1 (0.43) ESR1ESR2MAPTLMNAPDK2
SCHEMBL29407805 0.82 ESR1 (0.43) ESR1ESR2MAPTLMNAPDK2
SCHEMBL812773 0.82 ESR1 (0.43) ESR1ESR2MAPTLMNAPDK2
SCHEMBL23214358 0.81 ESR1 (0.42) ESR1ESR2MAPTLMNAPDK2
SCHEMBL29441936 0.81 ESR1 (0.42) ESR1ESR2MAPTUSP2LMNA
SCHEMBL20718777 0.81 ESR1 (0.42) ESR1ESR2MAPTUSP2LMNA
SCHEMBL23214350 0.80 ESR1 (0.40) ESR1ESR2MAPTLMNAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689487-B2 Polycarbonate copolymer, optical lens and film in which said polycarbonate copolymer is used, and method for producing said copolymer MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-06-23 US disclosed
US-20190119442-A1 POLYCARBONATE COPOLYMER, OPTICAL LENS AND FILM IN WHICH SAID POLYCARBONATE COPOLYMER IS USED, AND METHOD FOR PRODUCING SAID COPOLYMER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2019-04-25 US disclosed
EP-3441415-A1 POLYCARBONATE COPOLYMER, OPTICAL LENS AND FILM IN WHICH SAID POLYCARBONATE COPOLYMER IS USED, AND METHOD FOR PRODUCING SAID COPOLYMER Mitsubishi Gas Chemical Company, Inc. (JP) 2019-02-13 EP disclosed