SCHEMBL20724124

SCHEMBL20724124

C=CCn1c(=O)[nH]c(=O)n(CC(O)CC)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
CYP2C19 P33261 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GRIN1 Q05586 5/20 0.36
GRIN2B Q13224 5/20 0.36
ADORA2B P29275 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
PDE4A P27815 1/20 0.35
ADORA2A P29274 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12774670 0.87 CYP3A4 (0.57) CYP3A4ALDH1A1HTTKMT2ACYP1A2
SCHEMBL24495893 0.87 CYP3A4 (0.57) CYP3A4ALDH1A1HTTKMT2ACYP1A2
SCHEMBL15946190 0.81 CYP3A4 (0.50) CYP3A4ALDH1A1HTTKMT2ASMN1; SMN2
SCHEMBL19303759 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL12999576 0.80 CYP3A4 (0.48) CYP3A4ALDH1A1HTTKMT2ASMN1; SMN2
SCHEMBL157928 0.79 CYP3A4 (0.71) CYP3A4ALDH1A1KDM4EHTTCYP2C19
SCHEMBL12999579 0.79 CYP3A4 (0.47) CYP3A4ALDH1A1HTTKMT2ASMN1; SMN2
SCHEMBL20724113 0.78 CYP1A2 (0.34) CYP3A4ALDH1A1KDM4EHTTCYP2C19
SCHEMBL13661089 0.78 CYP3A4 (0.58) CYP3A4ALDH1A1KDM4EHTTCYP2C19
SCHEMBL11077876 0.77 CYP3A4 (0.68) CYP3A4ALDH1A1KDM4EHTTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202528-B2 Polymer and composition including same, and adhesive composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-02-12 US disclosed