Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.87 |
| ▸ | FLT4 | P35916 | 7/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635552 | 0.93 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL14635844 | 0.93 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL12479033 | 0.93 | PTK2 (1.00) | PTK2FLT4 | |
| Narmafotinib SCHEMBL12479576 | 0.91 | PTK2 (1.00) | PTK2FLT4 | |
| Narmafotinib SCHEMBL30354504 | 0.91 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL14635846 | 0.90 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL14576624 | 0.88 | PTK2 (1.00) | PTK2FLT4 | |
| SCHEMBL14635541 | 0.86 | PTK2 (0.86) | PTK2FLT4 | |
| SCHEMBL12478590 | 0.84 | PTK2 (0.85) | PTK2FLT4 | |
| SCHEMBL12478577 | 0.84 | PTK2 (0.85) | PTK2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675794-B1 | SELECTIVE FAK INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2019-02-13 | — | — | EP | disclosed |