Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15354452 | 0.89 | LRRK2 (0.47) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL21389693 | 0.86 | PIK3CD (0.43) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL21389719 | 0.86 | PIK3CD (0.43) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL179452 | 0.83 | PLK1 (0.42) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL250961 | 0.83 | PIK3CD (0.41) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL251804 | 0.83 | PIK3CD (0.41) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL179509 | 0.83 | PLK1 (0.42) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL179462 | 0.83 | PLK1 (0.42) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL217591 | 0.83 | PIK3CD (0.41) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 | |
| SCHEMBL218369 | 0.81 | ADORA2A (0.41) | PIK3CDPIK3R1ADORA2AADORA1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441392-A1 | A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | Intellikine, LLC (US) | 2019-02-13 | — | — | EP | disclosed |