SCHEMBL20725979

SCHEMBL20725979

CC(C)CCc1cc2cccc(Cl)c2c(=O)n1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 19/20 0.45
PIK3CG P48736 14/20 0.45
PIK3R1 P27986 11/20 0.45
ABCB11 O95342 1/20 0.45
TBXA2R P21731 1/20 0.45
HTR2A P28223 1/20 0.45
PIK3CA P42336 1/20 0.45
PIK3CB P42338 1/20 0.45
PDE3A Q14432 1/20 0.45
PIK3R2 O00459 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16116761 0.86 PIK3CD (0.42) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL16345901 0.85 PIK3CD (0.41) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL14649255 0.84 PIK3CD (0.44) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL16346401 0.84 PIK3CD (0.42) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL2599468 0.84 PIK3CD (0.42) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL14726533 0.81 PIK3CD (0.43) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL16591273 0.79 PIK3CD (0.54) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL16386791 0.78 PIK3CD (0.53) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL30343572 0.77 PIK3CD (0.54) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R
SCHEMBL29440942 0.77 PIK3CD (0.54) PIK3CDPIK3CGPIK3R1ABCB11TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3441392-A1 A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION Intellikine, LLC (US) 2019-02-13 EP disclosed