Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 11/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061490 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL20061616 | 0.84 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL15816351 | 0.83 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL15816350 | 0.83 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL12688658 | 0.82 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL9884034 | 0.81 | PIK3CD (0.62) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL14649443 | 0.81 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL14730049 | 0.80 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL14649365 | 0.80 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB | |
| SCHEMBL20061389 | 0.80 | PIK3CD (0.59) | PIK3CDPIK3CGPIK3R1PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441392-A1 | A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | Intellikine, LLC (US) | 2019-02-13 | — | — | EP | disclosed |