Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22604250 | 1.00 | NR1H2 (0.35) | NR1H2NR1H3PTPN1PDE4BUSP2 | |
| SCHEMBL29548240 | 1.00 | NR1H2 (0.35) | NR1H2NR1H3PTPN1PDE4BUSP2 | |
| SCHEMBL29548966 | 0.91 | USP2 (0.36) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL31234629 | 0.86 | USP2 (0.34) | NR1H2NR1H3PTPN1PDE4BUSP2 | |
| SCHEMBL2565648 | 0.86 | USP2 (0.34) | NR1H2NR1H3PTPN1PDE4BUSP2 | |
| SCHEMBL2565651 | 0.86 | USP2 (0.34) | NR1H2NR1H3PTPN1PDE4BUSP2 | |
| SCHEMBL18549712 | 0.85 | HSD17B10 (0.38) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL12480348 | 0.85 | HSD17B10 (0.38) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL18549658 | 0.85 | HSD17B10 (0.38) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL3428608 | 0.85 | HSD17B10 (0.38) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032936-A1 | LINCONSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT ADN FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |