Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269872 | 0.89 | NR1H2 (0.45) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL18084470 | 0.89 | NR1H2 (0.45) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL4864314 | 0.89 | NR1H2 (0.45) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL5761827 | 0.87 | PTPN1 (0.46) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL22543468 | 0.87 | PTPN1 (0.46) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL10058225 | 0.87 | PTPN1 (0.46) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL2995875 | 0.84 | HSD17B10 (0.47) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL443655 | 0.84 | HSD17B10 (0.47) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL26353928 | 0.84 | HSD17B10 (0.47) | NR1H2NR1H3NPC1PTPN1HSD17B10 | |
| SCHEMBL1486184 | 0.81 | HSD17B10 (0.58) | NPC1HSD17B10UCHL1SCN4AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032941-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-02-14 | — | — | WO | disclosed |