⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188997 | 1.00 | — | — | |
| SCHEMBL7893167 | 0.84 | — | — | |
| SCHEMBL7881656 | 0.84 | — | — | |
| SCHEMBL2638899 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6371156 | 0.82 | CPN1 (0.47) | — | |
| SCHEMBL364423 | 0.79 | — | — | |
| SCHEMBL22260255 | 0.79 | — | — | |
| SCHEMBL13326697 | 0.79 | — | — | |
| SCHEMBL17311181 | 0.79 | — | — | |
| SCHEMBL17311080 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019032863-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-02-14 | — | — | WO | disclosed |
| CN-103102344-B | Amino quinazoline derivative and salt thereof and using method | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2015-10-14 | — | — | CN | disclosed |