SCHEMBL20732179

CN[C@H](C(O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)NCCCC[C@@H](N)C(=O)O)C(C)C)C(C)(C)C)C(C)(C)c1cn(C)c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TUBB1	Q9H4B7	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24574908	0.88	TUBB1 (0.45)	TUBB1
SCHEMBL22307919	0.88	TUBB1 (0.45)	TUBB1
SCHEMBL22307917	0.88	TUBB1 (0.45)	TUBB1
SCHEMBL24574907	0.88	TUBB1 (0.45)	TUBB1
SCHEMBL24574485	0.83	TUBB1 (0.44)	TUBB1
SCHEMBL24574723	0.79	TUBB1 (0.45)	TUBB1
SCHEMBL24574538	0.78	TUBB1 (0.47)	TUBB1
SCHEMBL24574716	0.77	TUBB1 (0.48)	TUBB1
SCHEMBL20732182	0.76	TUBB1 (0.57)	TUBB1
SCHEMBL22309062	0.76	TUBB1 (0.57)	TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019031614-A1	ANTIBODY-DRUG CONJUGATES INCLUDING HEMIASTERLIN DERIVATIVE	大日本住友製薬株式会社	2019-02-14	—	—	WO	disclosed