Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20733275 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBMAPTALDH1A1KDM4E | |
| SCHEMBL22662832 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBMAPTALDH1A1KDM4E | |
| SCHEMBL7627401 | 0.79 | CXCR4 (0.50) | CXCR4SMN1; SMN2SIGMAR1CHRM2CHRM4 | |
| SCHEMBL2949018 | 0.78 | POLB (0.44) | SMN1; SMN2POLBALDH1A1THRB | |
| SCHEMBL1446208 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBMAPTALDH1A1KDM4E | |
| SCHEMBL7625818 | 0.78 | CXCR4 (0.44) | CXCR4SMN1; SMN2SIGMAR1POLBKDM1A | |
| SCHEMBL17599187 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBMAPTALDH1A1KDM4E | |
| SCHEMBL1421683 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBMAPTALDH1A1KDM4E | |
| SCHEMBL1447130 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBMAPTALDH1A1KDM4E | |
| SCHEMBL1446210 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2020-11-19 | — | — | US | disclosed |
| WO-2019030197-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361910-A1 | PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES | HRH3, HRH4, HRH1 | CXCR4 1262/4885SMN1; SMN2 4684/4885SIGMAR1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.