SCHEMBL20733751

SCHEMBL20733751

CC1(C)c2ccccc2-c2ccc3c4ccccc4c4nc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)nnc4c3c21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.34
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20733747 0.93 PTGER4 (0.32) PTGER4
SCHEMBL20733795 0.82 PTGER4 (0.34) PTGER4KDM4EATML3MBTL1
SCHEMBL14725785 0.81 KDM4E (0.36) PTGER4KDM4EATML3MBTL1
SCHEMBL15338001 0.80 KDM4E (0.41) PTGER4KDM4EATML3MBTL1
SCHEMBL19758578 0.80 PTGER4 (0.35) PTGER4KDM4EATML3MBTL1
SCHEMBL16406774 0.79 PTGER4 (0.35) PTGER4KDM4EATML3MBTL1
SCHEMBL19195993 0.79 KDM4E (0.38) PTGER4KDM4EATML3MBTL1
SCHEMBL15912243 0.79 KDM4E (0.35) PTGER4KDM4EATML3MBTL1
SCHEMBL19758617 0.79 PTGER4 (0.37) PTGER4KDM4EATML3MBTL1
SCHEMBL16283062 0.78 KDM4E (0.39) PTGER4KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230057590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-02-23 US disclosed
US-20190051842-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230057590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 PTGER4 1473/4885KDM4E 655/4885ATM 4475/4885
US-20190051842-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OXER1 PTGER4 1473/4885KDM4E 655/4885ATM 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.