Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 19/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 12/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 12/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 11/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545687 | 0.93 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20734026 | 0.93 | FGFR1 (0.39) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20486911 | 0.90 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29886181 | 0.90 | FGFR1 (0.56) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733966 | 0.89 | FGFR1 (0.60) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733910 | 0.89 | FGFR1 (0.50) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733904 | 0.88 | FGFR1 (0.47) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20734025 | 0.86 | FGFR4 (0.54) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20733941 | 0.86 | FGFR1 (0.46) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29546096 | 0.83 | FGFR1 (0.48) | FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384790-B | Fibroblast growth factor receptor inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2019029541-A1 | FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-02-14 | — | — | WO | disclosed |