Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 15/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.54 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071423 | 0.94 | FGFR4 (0.59) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL18897359 | 0.82 | FGFR4 (0.48) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071683 | 0.81 | FGFR4 (0.57) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653119 | 0.81 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL18897147 | 0.81 | FGFR4 (0.47) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL22420160 | 0.80 | FGFR4 (0.47) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL16071527 | 0.80 | FGFR4 (0.65) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL20733986 | 0.79 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL23653235 | 0.78 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL20734042 | 0.77 | FGFR4 (0.46) | FGFR4FGFR1FGFR2FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019029541-A1 | FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-02-14 | — | — | WO | disclosed |