⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20738688 | 1.00 | — | — | |
| SCHEMBL8282922 | 0.82 | — | — | |
| SCHEMBL681871 | 0.80 | — | — | |
| SCHEMBL29738290 | 0.80 | — | — | |
| SCHEMBL9963353 | 0.76 | KDM4E (0.37) | — | |
| SCHEMBL21515931 | 0.76 | — | — | |
| SCHEMBL978914 | 0.76 | — | — | |
| SCHEMBL3026028 | 0.76 | — | — | |
| SCHEMBL839685 | 0.76 | — | — | |
| SCHEMBL7382265 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190048421-A1 | BIOMARKERS OF RESPONSE TO HIF-2-ALPHA INHIBITION IN CANCER AND METHODS FOR THE USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-02-14 | — | — | US | disclosed |