Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900347 | 0.79 | MAPT (0.53) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL19900392 | 0.79 | MAPT (0.53) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL25689297 | 0.79 | MAPT (0.53) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL25689303 | 0.79 | MAPT (0.53) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL19919338 | 0.77 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL19919344 | 0.77 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL20735030 | 0.73 | KMT2A (0.32) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL20734954 | 0.73 | KMT2A (0.32) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL19900126 | 0.72 | MAPT (0.56) | KMT2AMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL19900172 | 0.72 | MAPT (0.56) | KMT2AMAPTMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-11-01 | — | — | US | disclosed |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | C5, CYP51A1, DDT | CHRM2 2297/4885CHRM4 2069/4885CHRM1 2836/4885 |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | CHRM2 2297/4885CHRM4 2069/4885CHRM1 2836/4885 |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | CHRM2 2297/4885CHRM4 2069/4885CHRM1 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.