Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32675078 | 0.92 | PTPN1 (0.50) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL22946818 | 0.92 | PTPN1 (0.50) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL6220927 | 0.90 | PTPN1 (0.50) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL6220930 | 0.90 | PTPN1 (0.50) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL24960703 | 0.89 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL15102739 | 0.89 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL806155 | 0.89 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL13250753 | 0.89 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL10177606 | 0.89 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL17850336 | 0.89 | PTPN1 (0.49) | PTPN1USP2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075357-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-04-18 | — | — | WO | disclosed |
| WO-2019032607-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019032612-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-02-14 | — | — | WO | disclosed |