SCHEMBL20738987

COCCC[C@@H](NC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C(C)C)C(C)(C)C)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TUBB1	Q9H4B7	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22111332	0.90	TUBB1 (0.40)	TUBB1
SCHEMBL22316484	0.90	TUBB1 (0.40)	TUBB1
SCHEMBL22346161	0.83	TUBB1 (0.43)	TUBB1
SCHEMBL22346164	0.83	TUBB1 (0.43)	TUBB1
SCHEMBL22316508	0.83	TUBB1 (0.43)	TUBB1
SCHEMBL20739117	0.83	TUBB1 (0.43)	TUBB1
SCHEMBL15430021	0.83	TUBB1 (0.41)	TUBB1
SCHEMBL13682371	0.83	TUBB1 (0.39)	TUBB1
SCHEMBL59703	0.83	TUBB1 (0.39)	TUBB1
SCHEMBL13682059	0.82	TUBB1 (0.45)	TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019031615-A1	HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME	大日本住友製薬株式会社	2019-02-14	—	—	WO	disclosed