SCHEMBL20739437

SCHEMBL20739437

C=C/C=C\C(=C/C=C)C1Nc2ccccc2N1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ CASP7 P55210 1/20 0.37
▸ GFER P55789 1/20 0.37
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22210737 0.84 MEN1 (0.36) MEN1GAAMAPTALOX15CASP1
SCHEMBL21186449 0.72 MEN1 (0.43) MEN1GAAMAPTALOX15KMT2A
SCHEMBL19154083 0.65 POLB (0.42) GAA
SCHEMBL22735008 0.63 — —
SCHEMBL21974294 0.62 GAA (0.32) GAAMAPT
SCHEMBL6422711 0.62 MEN1 (0.36) MEN1GAAMAPTALOX15CASP1
SCHEMBL21033784 0.62 AKT1 (0.39) MEN1MAPTALOX15KMT2A
SCHEMBL25665552 0.59 MAPT (0.31) MAPTALOX15
SCHEMBL18714078 0.59 — —
SCHEMBL23572391 0.58 AKT1 (0.35) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711091-B2 Light-emitting device and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-14 — — US disclosed
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711091-B2 Light-emitting device and method for producing same SCO2, SUN2, SLC18A2 MEN1 2564/4885GAA 2395/4885MAPT 386/4885
US-20190048131-A1 LIGHT-EMITTING DEVICE AND METHOD FOR PRODUCING SAME SCO2, SUN2, SLC18A2 MEN1 2564/4885GAA 2395/4885MAPT 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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