Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | PTGFR | P43088 | 4/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.60 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749914 | 1.00 | TBXA2R (0.60) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL20740218 | 1.00 | TBXA2R (0.60) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL20749941 | 0.91 | PDE4D (0.58) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL7666557 | 0.90 | PDE4D (0.51) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL7666551 | 0.90 | PDE4D (0.51) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL7866047 | 0.90 | PDE4D (0.51) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL17429905 | 0.90 | TBXA2R (0.61) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL13585407 | 0.87 | PTGFR (0.61) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL4246384 | 0.87 | PTGFR (0.61) | TBXA2RALDH1A1LMNAPTGFRPTGER1 | |
| SCHEMBL4246388 | 0.87 | PTGFR (0.61) | TBXA2RALDH1A1LMNAPTGFRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166918-B1 | METAL-CATALYZED ASYMMETRIC 1,4-CONJUGATE ADDITION OF VINYLBORON COMPOUNDS TO 2-SUBSTITUTED-4-OXY- CYCLOPENT-2-EN-1-ONES YIELDING PROSTAGLANDINS AND PROSTAGLANDIN ANALOGS | SCINOPHARM TAIWAN LTD (TW) | 2019-02-20 | — | — | EP | disclosed |