Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.43 |
| ▸ | CDK9 | P50750 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915329 | 0.89 | KDM4E (0.46) | CCNT1CDK9KDM4EALDH1A1GAA | |
| SCHEMBL2070453 | 0.85 | MAPT (0.35) | FFAR1CCNT1CDK9GAATSHR | |
| SCHEMBL4237467 | 0.85 | CMA1 (0.47) | CCNT1CDK9CHRM2CHRM1CHRM3 | |
| SCHEMBL30323683 | 0.85 | CMA1 (0.47) | CCNT1CDK9CHRM2CHRM1CHRM3 | |
| SCHEMBL1011307 | 0.83 | MAOB (0.53) | FFAR1CYP2D6 | |
| SCHEMBL12082470 | 0.82 | CCNT1 (0.40) | FFAR1CCNT1CDK9ALDH1A1HDAC1 | |
| SCHEMBL915498 | 0.82 | GGPS1 (0.45) | CCNT1CDK9KDM4EALDH1A1GAA | |
| SCHEMBL3390402 | 0.81 | CCNT1 (0.46) | CCNT1CDK9HDAC1TSHR | |
| SCHEMBL10867669 | 0.79 | CETP (0.52) | KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL27233590 | 0.78 | KMT2A (0.46) | CCNT1CDK9KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732915-B1 | SCHWEINFURTHIN ANALOGUES | UNIV IOWA RES FOUND (US) | 2016-01-06 | — | — | EP | disclosed |
| US-20110319481-A1 | SCHWEINFURTHIN ANALOGUES | Government of the United States of America, National Institute of Health (US) | 2011-12-29 | — | — | US | disclosed |
| US-7902228-B2 | such as: 3-Deoxyschweinfurthin B; anticancer assay; e.g. breast cancer or a cancer of the CNS or renal system diagnosis | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2011-03-08 | — | — | US | disclosed |
| US-20080227852-A1 | SCHWEINFURTHIN ANALOGUES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA | 2008-09-18 | — | — | US | disclosed |
| US-7358377-B2 | such as: 3-Deoxyschweinfurthin B; tested and were found to have anti-cancer by NCI 60-cell line anticancer assay; e.g. breast cancer or a cancer of the CNS or renal system | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2008-04-15 | — | — | US | disclosed |
| US-20080015232-A1 | SCHWEINFURTHIN ANALOGUES | US GOVERNMENT - SECRETARY FOR THE ARMY | 2008-01-17 | — | — | US | disclosed |
| EP-1732915-A2 | SCHWEINFURTHIN ANALOGUES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092878-A2 | SCHWEINFURTHIN ANALOGUES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015232-A1 | SCHWEINFURTHIN ANALOGUES | ERH, HRAS, HNRNPH1 | FFAR1 3273/4885CCNT1 1619/4885CDK9 2925/4885 |
| US-20080227852-A1 | SCHWEINFURTHIN ANALOGUES | ERH, HRAS, HNRNPH1 | FFAR1 3273/4885CCNT1 1619/4885CDK9 2925/4885 |
| US-20110319481-A1 | SCHWEINFURTHIN ANALOGUES | ERH, HRAS, HNRNPH1 | FFAR1 3273/4885CCNT1 1619/4885CDK9 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.